Food allergies and how scientists may be able to reverse them by targeting the gut bacteria.

Food allergies and how scientists may be able to reverse them by targeting gut bacteria.

Food allergies can be frustrating, causing inflammation in the gut and the rest of the body. At its worst, allergies can be life-threatening with anaphylaxis.

A bacterial compound called butyrate that’s made by healthy microbiomes has shown promise against allergic reactions in lab tests, but it’s nasty to take orally. Scientists are looking at ways to use this compound to treat and potentially reverse food allergies.

This information will be released at the fall meeting of the American Chemical Society (ACS) this year.

The discovery of this approach has come after attempts of making similar changes using fecal transplants failed to eliminate the allergies it was used to treat. Treatment methods that are now under trial include injections and also oral administration.

Read this article to find out more.

Food allergies can be reversed in mice by targeting the microbiome

Published August 22, 2022 |

Although many people with dietary allergies experience mild symptoms when exposed to triggering foods, some face potentially fatal consequences. A bacterial compound called butyrate that’s made by healthy microbiomes has shown promise against allergic reactions in lab tests, but it’s nasty to take orally. Today, scientists describe a more palatable way to deliver this compound and report that their “polymeric micelles” are effective against peanut allergies in mice. The treatment could someday counteract many types of food allergies and inflammatory diseases.

The researchers will present their results at the fall meeting of the American Chemical Society (ACS).

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